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Mounted atop a Soyuz U rocket, the Progress 46 space freighter blasted off from Baikonur Cosmodrome at 6:06 p.m. EST.
About 10 minutes later, it was zooming around the planet in low Earth orbit, its solar arrays and navigation antenna successfully deployed.
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The launch was closely watched because a Progress freighter was destroyed in an Aug. 24 Soyuz U launch failure. An investigation into that accident cleared the way for the Oct. 30 launch of another Soyuz U rocket on a return-to-flight mission.
The Progress 46 spacecraft will carry out a series of trajectory correction burns over the next two days. It is expected to dock at the International Space Station at 7:08 p.m. EST Friday. Live NASA TV coverage will pick up here in The Flame Trench at 6:30 p.m. EST.
The station now is staffed by U.S. astronauts Dan Burbank and Don Pettit, European Space Agency astronaut Andre Kuipers, and three Russian cosmonauts: Anatoly Ivanishin, Anton Skaplerov and Oleg Kononenko.
The ISS has been staffed continuously since the first expedition crew boarded the outpost on Nov. 2, 2000.
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